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Knockout of the de novo DNA methyltransferase DNMT3A in human induced pluripotent stem cell (iPSC)-derived cardiomyocytes within engineered heart tissues (EHTs) causes mitochondrial dysfunction, impaired glucose metabolism, and intracellular lipid accumulation under baseline conditions

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Pecikoza U, Tomi M, Nasti K, Micov A, Stepanovi-Petrovi R

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Intramuscular Injections Methylcobalamin injections are a more direct and rapid way to increase your vitamin B12 levels