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Take it daily regardless of whether you exercise that day

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Intramuscular administration allows B12 to bypass hepatic metabolism and enter systemic circulation directly, which is why this route differs from oral supplementation

Other issues, like atrophic gastritis (a thinning of the stomach lining), reduce the production of stomach acid, which is essential for releasing B12 from food

Vitamin B12 IV Infusion This method delivers a high dose of B12 directly into the bloodstream

In SURMOUNT-1, nausea occurred in 24.6% of participants on 5mg, 33.3% on 10mg, and 31.0% on 15mg