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82 Milk extracellular vesicles may be loaded with drugs, vaccines or nucleic acids for therapeutic and gene editing applications

Although the mechanism by which oxidizing agents is distinct from ionizing radiation, conditions like severe sepsis and septic shock also create an oxidation-rich environment that leads to the depletion of natural cellular antioxidants (such as glutathione) and contributes to cellular injury and death

The available X-ray crystal structures implicate histidine 571 (that arises from the opposing subunit) as being responsible for this deprotonation, as it is the only residue that is proximal to the C154-C159 pair that has the capacity to act as a general base (Figure 2)

45 Advances in genome-scale imaging have provided deeper insights into cell profiling and spatial tissue mapping

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More importantly, different EV cargoes have significant synergistic effects in driving inflammation and tumor development