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Souza et al

We've looked at serotonin in detail at our CBD and serotonin review

In addition to increasing levels of superoxide radicals, oxidative stress in diabetes is caused by the alterations in concentration of enzymes such as catalase, SOD, and glutathione peroxidase (GSH-Px)

Other routes of administration such as taking vitamins orally are limited by many factors including time to absorption, suboptimal absorption rates due to digestive dysfunction, detoxification processed limiting dose available to the rest of the body, and often poor bioavailability of active ingredients found in common supplement brands

Int J Obes (2001) 25(12):17828

Hamed et al., 2017)