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Despite this, cyanocobalamin has been increasingly criticised in recent years, due to the following reasons: Toxicity: cyanocobalamin is often claimed to be toxic, as the cyano group form the poison cyanide

Unlike traditional supplements, patch-based nutrients are designed to enter systemic circulation without passing through the gastrointestinal tract, potentially improving the proportion of a substance that reaches the bloodstream

Dysbiosis is considered a pro-inflammatory state often depleting some key species that have significant functions in maintaining the ecological balance of the microbial community

Vitamin B3, or niacin, keeps skin hydrated and inflammation at bay

& Merz, K