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De Zambotti M, Covassin N, De Min Tona G, Sarlo M, Stegagno L

Variable expression of endothelial NO synthase in three forms of rat pulmonary hypertension

Intestinal diseases such as Crohns and celiac disease could cause problems

doi: 10.1371/journal.pone.0028330 [DOI] [PMC free article] [PubMed] [Google Scholar] 372

This clinical study demonstrates that NAD+ declines with age in humans, highlighting age-associated shifts in redox balance and NAD+ metabolism that may contribute to aging and disease