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10.1089/ars.2017.7249 294 SalehH

LOXL2 is a Cu-dependent amine oxidase that plays a critical role in matrix remodeling and fibrosis (Wen et al., 2018)

Because of these capacities, dermatologist Dr

Their action signals the cell to modulate its response, through the recruitment of endogenous coping mechanisms, among which are an increased synthesis of antioxidants and of electrophile quenchers, the transcription of the necessary gene products and the production of reducing cofactors such as NADH/NADPH and ascorbate

For example, SIRT4 can inhibit tumorigenesis by inducing autophagy [169], while Smarcd3 can establish aggressive lipid metabolism remodelling [170]

Zhang, X.-D