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They mainly contribute to the induction of genome instability, the counteraction of host immune responses, the resistance of cell death and the promotion of tumor development, progression and invasiveness

The co-occurrence of BD with menstrual cycle-related disorders such as premenstrual dysphoric disorder (PMDD) appears to have a noteworthy impact on these patients, leading to greater chronobiological disruptions across the follicular and luteal phases of the menstrual cycle [360]

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J Clin Endocrinol Metab 89 : 21192126

Although the intestine is completely formed and functional at hatch, it continues to develop and mature as the chick transitions to exogenous nutrient sources (132)