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WangKZZhuJDagdaRKUechiGCherraSJ3rdGusdonAMet alERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: implications for Parkinsons disease

Expert Opin On Pharmacotherapy

doi: 10.1186/s40246-024-00626-4 139 LiangPXuYZhangXDingCHuangRZhangZet al

Disease states of GH excess (e.g., acromegaly) and GH deficiency (e.g., congenital isolated GH deficiency) are characterized by increased and decreased GH, IGF-I and insulin levels, respectively, where the GH/IGF-I relationship is reflected by a primary association

This typically involves periodic blood tests, imaging studies, and fibrosis assessment (using FIB-4 and ELF scores as outlined in NICE NG49) to monitor disease progression