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There are two critical pathogenesis hallmarks for TB: the escape of Mtb from lysosome destruction and the limited drug delivery into the Mtb-infected macrophages, which contribute to the 612-month-long TB therapy involving multiple drugs that always cause side effects and drug-resistant mutants ( Except for facilitating the phagolysosome and polarization function of macrophages, Se NPs can also control inflammatory responses by regulating macrophages

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doi: 10.7326/0003-4819-137-12-200212170-00007

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