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Results Subjective drug effects Subjective effects over time on the VAS are shown in Fig

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Repurposing existing drugs: Identification of irreversible IMPDH inhibitors by high-throughput screening

The specific analysis of CSF samples from amnestic MCI and AD subjects identified the early carbonylation of extracellular chaperones, suggesting that dysfunction of these pathways is initiated many years before severe dementia is diagnosed and might represent a reliable biomarker for pathology onset and progression (311, 318,319)