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The current adult weight-reduction label allows 7.2 mg after at least four weeks at 2.4 mg when additional loss is clinically indicated, and STEP UP measured more weight loss at 7.2 mg than at 2.4 mg. Side effects rise along the same curve

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PMID: 16987039

Disclosures: Laurent Castera: Nothing to Disclose, Ming-Lung Yu: Abbvie, Gilead and Roche diagnostics.: Grant/Research Support, Abbott, Abbvie, Gilead, Roche and Roche diagnostics: Consultant, Abbvie, BMS, Gilead, Roche and Roche diagnostics: Speaking and Teaching, Maria Buti: Nothing to Disclose, Nothing to Disclose, Jinlin Hou: Nothing to Disclose, Frida Abramov: Gilead Sciences, Inc: Employee, Gilead Sciences, Inc: Stock - publicly traded company, Hongyuan Wang: Nothing to Disclose, Ben Da: Nothing to Disclose, DANA TEDESCO: Gilead Sciences, Inc.: Employee, Leland Yee: Nothing to Disclose, John Flaherty: Nothing to Disclose, Harry Janssen: Gilead Sciences: and consultant, Gilead Sciences: Grant/Research Support, GlaxoSmithKline: Grant/Research Support, Janssen: Grant/Research Support, Roche: Grant/Research Support, Vir Biotechnology Inc.: Grant/Research Support, Aligos: Consultant, Gilead Sciences: Consultant, GlaxoSmithKline: Consultant, Grifols: Consultant, Roche: Consultant, Vir Biotechnology Inc: Consultant, Precision Biosciences: Consultant, Milan Sonneveld: Nothing to Disclose

Huang Y, Lin J, Xiong Y, Chen J, Du X, Liu Q