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Open Biol

Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

McDermott, M

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This evidence reflects the role of the mitochondria as key targets for promoting apoptosis and also provides evidence for the role of other organelles like acidocalcisome as targets to store divalent Ca 2+ and heavy cations, Fe 2+ and Zn 2+ , which could be able to capture quinoline compounds via coordination binding

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