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Adapting to insulin resistance in obesity: role of insulin secretion and clearance

Checkpoint inhibitors (Programmed Cell Death Protein 1/Programmed Death-Ligand 1 (PD-1/PD-L1), Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4)) are already well established in oncology, but their role in radiation-induced injury is dual