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at intervals of 15 min to assess the effects of compounds alone

The hypothalamus produces endogenous GHRH in a pulsatile fashion, with the most significant release occurring during deep sleep stages

Tuft cells express succinate receptor 1 on their surface which detects the presence of this in SCFA in the gut lumen stimulating downstream signalling pathways and leading to a type-2 IR (Nadjsombati et al