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Carnitine palmitoyltransferase 1 CPT1, an enzyme on the mitochondrial outer membrane, is key to FAO

Increased levels of ROS and lower expression of glycolysis-associated genes, including glucose transporter-1 (GLUT1), phosphofructokinase (PFK), and lactate dehydrogenase A (LDHA), have been reported in granulosa cells of PCOS women compared with non-PCOS women, indicating that the low oocyte competence in PCOS may be associated with mitochondrial dysfunction and abnormal glycolysis [40]