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Haroon HB, Mukherjee D, Anbu J, Teja BV (2021) Thiolated chitosan-centella asiatica nanocomposite: a potential brain targeting strategy through nasal route

The optimal formulation consisted of 0.25% glabridin, 0.47% poloxamer 188, and 0.11% polyvinylpyrrolidone K30

HGF protects endothelial cells against apoptosis in cerebral ischemia animal models and prevents the associated learning and memory dysfunctions (Date et al., 2004)

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However, during inflammatory reactions, exposure of macrophages to interferon (IFN) and TNF results in the activation of the inducible isoenzyme of NOS (iNOS), which increases up to 10 times the levels of nitric oxide

The RDA of biotin for adults 19 years and older is 30 ug biotin daily [60]