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Because TCA cycle function is disrupted and mitochondria are uncoupled because of freezing and thawing (Acin-Perez et al, 2020

This approach has led to one of the early programmes for inhaled insulin and eventually to FDA-approved inhaled l-DOPA for the treatment of Parkinson disease 106,107

The diameter grows from approximately 5 mm at birth to 910 mm in a 20-year-old

Int Rev Chem Eng 3:320 Ilyasov I, Beloborodov V, Antonov D, Dubrovskaya A, Terekhov R, Zhevlakova A, Saydasheva A, Evteev V, Selivanova I (2020) Flavonoids with glutathione antioxidant synergy: influence of free radicals inflow