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10.1056/NEJMoa2206038 29 Johnson-ArborK.DubeyR

M.CorbineauF.BouteauH

Hepatology 49:13751384

Parthanatos Another mitochondrial RCD pathway that has been cited to be activated following GA exposure is parthanatos, a pathway activated by genotoxic cellular damage

The MTHFR gene that codes for this enzyme has the potential to mutate, which can either interfere with the enzyme's ability to function normally or completely inactivate it