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During autophagy initiation, the MAMs region is enriched with key autophagy precursor proteins, including double FYVE-containing protein 1 (DFCP1) and WD repeat domain phosphoinositide-interacting protein 1 (WIPI1)

An indirect test refers to the antibody being detected in the serum

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Mice were monitored for survival and euthanized if they exhibited severe disease symptoms, including hemiparesis or a loss of more than 20% of body weight

Its effects extend to hepatic improvement, with decreased liver fat content and fibrosis-related markers such as fibroblast growth factor 21 (FGF-21) and procollagen type III (Pro-C3), suggesting a potential to reverse steatosis and early fibrosis

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