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Pyrshev et al

intend to file a patent application based on the findings reported in this manuscript

You might also experience muscle weakness, joint pain, sensitivity to chemicals or strong smells, or premature signs of aging like dull skin

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Under hypoxic conditions, autophagy has been shown to promote degradation of such aggregates through the CHIP protein (C terminus of Hsc70-interacting protein), suggesting it can be a key element to selectively reduce mutp53 GOF under hypoxic conditions (Maan and Pati, 2018)

Elevated ROS levels, especially in the early stages of cancer, can contribute to carcinogenesis by promoting genomic instability, mitogenic signaling pathways, and the NF-B pathway, among others [26]