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4CD, green fluorescence in the UVB-induced group was much brighter, showing that intracellular ROS levels were 4.0 times higher than those of the control group

No finished-drug approval, no active IND, and no FDA-registered human clinical trials as of April 2026

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Significant attention has been placed on blocking cystine uptake 17,7276 or cysteine production from methionine via the transsulfuration pathway 9,7779

For analysis of spheroid formation of HCT116 cells, the shRNA-resistant expression vector of FLAG-PGRMC1 or an empty vector was transfected as described above

Stereotactic ablative body radiotherapy/stereotactic body radiation therapy (SABR/SBRT) precise, high-dose radiation therapy given in a small number of fractions