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A poor nitrogen source can result in a low growth rate, which itself might affect the rate of GSH synthesis non-specifically

supplying substrate for Fe-S cluster production [36]

[PubMed] Jo, A.O., D.A

The increased expression of SAT1 promotes the depletion of spermidine and spermine, which leads to mitochondria-mediated apoptosis, and increases the sensitivity of drug-resistant cells to cisplatin-induced apoptosis (Mandal et al., 2015)

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