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Description

These figures describe reference research protocols only and are provided strictly for research use, not human use

Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

This page has been reviewed for clinical accuracy, safety, and alignment with current FDA guidance, ADA 2026 Standards of Care, and WHO GLP-1 guidelines for all information related to semaglutide, tirzepatide, retatrutide, and GLP-1/GIP weight loss therapy.