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2023 Feb 8;76(3):e439-e449

In addition, those who take certain medications may be at increased risk for B12 deficiency, per Healthline

The report says the most common reactions were injection site reactions (50.2%), fatigue (38.2%), headache (38.9%), muscle pain (33.2%), nausea (14.2%) and fever (9.0%)

The last step in the production of adrenalin is the methylation of nor-adrenalin to produce methyl-nor-adrenalin or adrenalin by the enzyme Norepinephrine-N-methyl-transferase