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Manganese-containing superoxide dismutase (Mn-SOD) typically converts superoxide to H 2 O 2

SPECT/MRI dual-modality imaging based on Mb@ 177 Lu/Gd-NTs can not only clearly show the anatomical location of tumors, but can also quantitatively display the drug biodistribution in real time, which is helpful to determine the administration time of external beam irradiation