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10.1093/hmg/ddv372 Hum

For instance, P115 and GRASP65 trigger apoptosis via the ERK/p53/PUMA pathway or Fas-mediated signaling, respectively, whereas Bruce and GAAP decrease apoptosis via caspase-9, Smac and p53 inhibition, and Ca 2+ signaling downregulation [93]

10.3389/fpls.2015.00505 Front

and exploring regulatory strategies targeting the microbiome-immune-oxidative axis for microecological imbalance phenotypes

Intermittent hypoxia improves atrial tolerance to subsequent anoxia and reduces stress protein expression

Tumor ECM is substantially different in structure and composition and exhibits fibroblastic/myofibroblastic infiltration, followed by the considerable buildup of collagenous matrix or desmoplastic stroma, obstructing anti-cancer drug delivery to cancer cells [251, 252]