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212 men with PSA progressing PCa (average age 74.5 years) managed with surveillance were given a phytochemical rich supplement uniquely containing both standardised extracts and whole purified organic ginger, cranberry, pomegranate, turmeric, broccoli and green tea

Zhang M, Wang A, Xia T, He P (2008) Effects of Fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-kappaB in primary cultured rat hippocampal neurons

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The multifaceted mechanism of action of 5FU involves direct incorporation of its metabolites into DNA (FdUTP) and RNA (FUTP), as well as inhibition of thymidylate synthase (TS) via FdUMP 4,5 , making it more difficult to identify rational combination partners that would enhance clinical responses without eliciting adverse systemic toxicity

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To prolong the residence period of formulation and combat nasal clearance, NEs can be converted to mucoadhesive systems