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Differentiation of GFP-Bcl-2-engineered mesenchymal stem cells towards a nucleus pulposus-like phenotype under hypoxia in vitro

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Inhibition of Piezo1 by GsMTx4 in the cerebral cortex of rats after ischemia/reperfusion attenuates cell viability inhibition and apoptosis, increases intracellular calcium levels, and enhances calpain activity ( in vitro , but has little effect on normal physiological processes in vivo , yet has a strong therapeutic effect on pathology