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Elevated levels of ROS increase the incidence of mtDNA mutations [41], and the accumulation of induced mtDNA mutations as well as restricted DNA repair capacity, together with errors during replication, lead to increased DNA damage and chromosome damage [42, 43]

10.2169/internalmedicine.39.547 45

10.1080/01480545.2023.2291983 59 DixitR

In a typical micelle the molecules are arranged in a sphere with the hydrophobic tails of the surfactant(s) preferentially located inside the sphere and the hydrophilic heads of the surfactant(s) preferentially located on the outside of the micelle where the heads preferentially interact with the more polar solvent

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Hence, GSH-CDs synthesized at a ratio of 1:1 exhibited outstanding antioxidant enzyme activities, providing a favorable basis for alleviating IVDD caused by oxidative stress