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the pharmaceutical composition comprises at least one compound of Formula II, or tautomers, stereoisomers, salts, solvates or hydrates thereof

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Medications, like insulin, are effective when they're injected into the fatty tissue just below the skin

We discuss how copper also plays a key role in proteostasis and interacts either directly or indirectly with many of the key aggregate-prone proteins implicated in ALS, such as TDP-43, C9ORF72, SOD1 and FUS as well as the effect of their aggregation on copper homeostasis

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