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Similarly, consideration of the key degradation pathways used by cells shows that proteasome inhibition activates macroautophagy 11 , whereas autophagy inhibition impairs flux in the ubiquitinproteasome pathway 12 (Fig

The role of glutathione in cancer

10.11138/fneur/2016.31.1.007 37 BrandesN.SchmittS.JakobU

Quercetin can also induce the production of the antioxidant enzyme heme oxygenase-1 (HO-1), thereby enhancing cellular defense against oxidative damage (43)