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IDH1 mutations cause significant metabolic changes, suggesting that tumor cells rely on specific metabolic pathways to complete cell biological processes

Contrarily, in a shorter placebo-controlled study with healthy individuals, daily supplementation of 50 mg ( n = 32) or 100 mg ( n = 33) riboflavin showed no reduction in free thiols compared to placebo ( n = 34) 53

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Li et al used tetrahedral framework nucleic acid (tFNA) to synthesize tFNA-Cur, a nanoparticle that can deliver the natural compound curcumin to the bone marrow, thereby enhancing the bioavailability and stability of curcumin