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For instance, a study published in the journal Antioxidants found that individuals who took oral glutathione supplements showed increased levels of the antioxidant in their bloodstream, suggesting that oral supplementation is effective

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Increased NFE2L2 activation, in turn, upregulates the synthesis of GSH, which detoxifies NAPQI, and hence protects against APAP hepatotoxicity

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J Pathol (2020) 251(3):22848