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doi: 10.1016/j.jhep.2012.02.036

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This phosphorylation serves as a physiological brake that directly inhibits RIPK1 kinase activity in response to TNF, and prevents TNF-induced RIPK1 kinase-dependent cell death

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Despite these hemoglobin-based oxygen carriers (HBOCs) having a high oxygen carrying capacity, their stability is poor, and most of them are only useful for intravascular imaging