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In Parkinsons disease (PD) models, exercise increases the density of dendritic spines in medium spiny neurons (MSNs) in the striatum, thereby improving motor dysfunction (Palasz et al., 2019)

10.3390/molecules26082347 80 FissehaN.HammesoW

Mitochondrial dysfunction in chemotherapy-induced peripheral neuropathy (CIPN)

However, modern research has dispelled this concern

Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease.Insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker for this dementing disorder