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The Role of Dopamine Another group of researchers set out to tackle the problem of why we find drinking water so rewarding when were thirsty (Augustine at al., 2019)

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Methylation Capacity Second, NNMT inhibition affects cellular methylation capacity: SAM is required for hundreds of methyltransferase reactions throughout the cell, and NNMT's consumption of SAM can deplete this critical resource, while the SAH produced by NNMT is a potent product inhibitor of many methyltransferases

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