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Meanwhile, a complex feedback system can regulate GH secretion, including IGF-1, leptin, and ghrelin along with the central nervous system

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The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]

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[DOI] [PubMed] [Google Scholar] 92.Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Jagic V., Turkovic B., Rotkvic I., Mise S., Zoricic I., et al