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This slows down the transmission of electrical signals in the brain and peripheral nervous system, manifesting clinically as slowed processing speed, memory recall issues, and peripheral neuropathy (tingling or burning sensations in the hands and feet)

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The pharmacology of mechanogated membrane ion channels

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However, it remains unclear how genetics affect the abundance of expression features

In addition, alcohol exerts some harmful effects through its breakdown (i.e., metabolism) and the resulting toxic compounds, particularly in the liver, where most of the alcohol metabolism occurs (Lieber 1992, 2000)