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The available findings suggest that silymarin: Can positively influence LDL and VLDL cholesterol levels Significantly increased HDL cholesterol (the so-called "good cholesterol") in studies Can improve oxidative status in the bloodstream Can counteract the reduction of glutathione in the liver caused by a high-cholesterol diet These findings come from clinical studies that were, however, in some cases methodologically heterogeneous

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Although hotspot mutation analysis is widely used in clinical and research settings, it is characterized by some limitations that may reduce sensitivity and specificity in cancer diagnosis and prognosis: i) some cancer cells may lack detectable mutations due to intratumor heterogeneity

Wu, L., et al

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These data confirmed that H 2 O 2 induced apoptosis in MC3T3-E1 cells