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This paper did not report baseline PASI absolute scores for these three trials, precluding firm conclusions about the benefit of the treatment (Clark 2019)

DOI: About the Author: Ed Van Harmelen is the founder of Youth & Earth and a passionate advocate for biohacking and anti-ageing since 2017

Therefore, there is a need for homogenization of the methodology

Middeke et al., 1997

ASK1, also known as MAP3K5, activates the downstream p38-JNK1/2 signalling pathway, thereby promoting inhibition of lipid and glucose metabolism 34,35,36 and driving a strong inflammatory response 37