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Causes of hyperhomocysteinemia in patients with chronic kidney diseases

Mercapturic acid derivatives ( N -acetyl-cysteine adducts) have been used as biomarkers of exposure to many exogenously derived chemicals Citation[108112] and endogenously derived bioactive substances Citation[6,113115]

Amide reduction occurs by nucleophilic addition of hydride ion to the amide carbonyl group, followed by expulsion of the oxygen atom as an aluminate anion leaving group to give an iminium ion intermediate

By adding N-acetylglucosamine to glycoproteins, GCNT3 facilitates the production of mucin-type O-glycans, which are essential for the structural integrity and diverse functional roles of mucins

Premenopausal status confirmed by clinical evaluation

*Correspondence: Jihong Liu, [email protected] These authors have contributed equally to this work Present address: Jingyu Song, Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China This article was submitted to Reproduction, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers