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Using the intranasal method in animal models, researchers have successfully reduced stroke damage, reversed Alzheimers neurodegeneration, reduced anxiety, improved memory, and delivered neurotrophic factors and neural stem cells to the brain

Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer

Plant Foods Hum Nutr 62:139144

Dig Liver Dis (2014) 46:52734

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Other routes of administration such as taking vitamins orally are limited by many factors including time to absorption, suboptimal absorption rates due to digestive dysfunction, detoxification processed limiting dose available to the rest of the body, and often poor bioavailability of active ingredients found in common supplement brands