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The fact that Yap1 deficiency extends the egtA phenotype indicates that in wild-type, EGT limitation is partially compensated by other detoxification mechanisms that require activation by Yap1

Thus, Pap1 suffers two waves of oxidation, the former being very fast (lasting only 2 min after 0.5 mM extracellular peroxides) and the second being more sustained (starting 3040 min after stress imposition)

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To measure their actual stiffness, the gels were immersed in PBS and force was measured on a NanoWizard three NanoOptics atomic force microscope (JPK Instruments, Berlin, Germany)

(China) and validated for authentication using the short tandem repeat (STR) method

[23] The concentration of mercury in any given fish depends on the species of fish, the age and size of the fish and the type of water body in which it is found