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doi: 10.1111/jpc.13659 21 ThomasCDurand-ZaleskiIFrenkielJMirallieSLegerACheillanDet al

Additionally, a large survey of over 2000 transmasculine patients on TRT revealed the following: 33.3% developed acne with injected testosterone 48.6% experienced acne with transdermal testosterone So while incidence varies, multiple studies suggest variables like dosage, duration, and genetics impact acne risk