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Search strategy and selection criteria This review adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to ensure methodological rigor

Interestingly, substituting the amino acids with alanine enhanced the peptides inhibitory ability (Table 1)

Immunity 2023;56:2699718.e11

We demonstrate that SFN does not change immune synapse maturation as determined by clustering of CD3 and the adhesion molecule LFA-1, but it inhibits the activation of untransformed human T-cells, in particular their proliferation and the production of T H 17-related cytokines

Estrogens are produced through metabolic steroid pathways in ovaries, the adrenal cortex, adipose tissue, testes and the placenta (Miettinen et al., 2000

While considering the ovary, the term mild dysfunction indicates the size of the ovary which is normal/nearly normal and mild injury to the ovarian serosa