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They are therefore less likely to experience irritation

Bonovas S, Lytras T, Nikolopoulos G, Peyrin-Biroulet L, Danese S

Fortunately, you cannot overdose on vitamin B12, as it is water-soluble, so adding more is not harmful

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MAO-A is more dominant in the heart, platelets, gut, and certain neurons, while MAO-B is prevalent in astrocytes and specific brain regions, as well as in the heart, intestines, kidneys, and blood vessels.[ref][ref][ref] Variants in the MAOA gene sometimes called the warrior gene can affect neurotransmitter levels and have been linked to changes in mood, aggressiveness, and response to antidepressants

Importantly, microglia can directly induce excitotoxicity by releasing glutamate (364, 373)