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In neurological models, its potential neuroprotective activity against oxidative stress is being investigated

For example, colonization of germ-free mice with Bacteroides thetaiotaomicron (191) or Escherichia coli Nissle 1917 (EcN) (192) led to up-regulation of genes encoding for proteins such as small proline-rich protein-2 (sprr2a) and ZO-1 involved in improving cellular adhesion

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