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The addition of exogenous recombinant DUSP3-WT for 30 min and 1 h promoted dephosphorylation of Y29, Y67, and Y271 residues of NPM, whereas these reactions are reversed in the presence of Na 3 VO 4 treatment, a potent pan inhibitor of PTPs (Figure 2D)

Thus this dip in the eGFR reflects favorable hemodynamic changes in the glomerulus

Free Radic Res30247252

Front Mol Neurosci (2023) 16:1113081

Accordingly, production of the endogenous antioxidant glutathione (GSH) by glial cells within the brain [8], particularly astrocytes [8,9,10], is a critical function, as most antioxidants are unable to cross the blood brain barrier