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Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization

Likewise, the suppressor oncogene p53 is capable of suppressing the activity of the IGF-1R promoter as well as lowering the endogenous levels of IGF-1R mRNA (Werner et al, 2000)

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In addition to urate transport inhibitors, xanthine oxidase inhibitors, as the most popular drug candidates, have attracted a lot of attention (Figure 2)